My Security setup that I've been using for the past two months:

Windows 8 Pro (patched upto date)
Avast Free antivirus v7
Online Armor Free Firewall v6

Firefox 19.0.1 with No-script, LastPass, AdblockPlus, WOT, BitDefender Traffic Light, Avast WebRep.
Sandboxie 3.76 Free version

MBAM and SAS for on demand scanning.